Current areas of focus

ICONIC has taken practical steps towards establishing activities in several areas recognised as being fundamental for developing science and its application to improving people’s lives. As a reminder, so far, activities have been carried forward around the following critical themes:

1. Building broader capability and more robust capacity for excellence in research and practice in Africa, with the longer-term ambition to develop a high-quality, context-specific research programme in this region;
2. Facilitating international collaboration and developing activities in the area of childhood cancers, with the ambition to create a Community of Practice focused on diet, nutrition, physical activity and cancer in children, teenagers and young adults (CTYA) that seeks to align research and communication to advance the adoption of essential practices and better inform care for young cancer patients;
3. Establishing the particular role played by professional nutritionists in establishing school meals as a system to improve the health of school children as well as become a vehicle for broader education on the nature and origin of foods and diets, their biological functions, their relationship to health, social structures, economics and more general social connections.
4. Developing a framework for establishing prehabilitation (in terms of personalised management of exercise, nutrition and psychological support before the start of definitive treatment) formally and in the context of quality implementation science.

Capacity building in Africa

While the incidence of cancer is rapidly increasing in LMICs and changing dietary patterns play an important role, grant proposals on nutrition and cancer submitted by LMICs scientists rarely qualify for funding. Working with Wageningen University and a newly formed group of African scientists within the African Nutrition Society, Cancer and Nutrition in Africa (CANA), the aim has been to develop an online course to improve grant writing capabilities across Africa in the first instance, as an imperative for the development of a high quality, relevant and context specific research programme in this region. The longer-term ambition is to develop a series of studies across the continent using standardised and validated methodologies that together will create the equivalent of an EPIC (European Prospective Investigation into Nutrition and Cancer) for Africa.

The Cancer and Nutrition Epidemiology in Africa online grant writing course is based on experience of similar courses within Wageningen University and intends to cover various aspects of grant writing such as formulating a research question, designing the most appropriate study, calculating study size, planning and budget, as well as other training skills relevant for grant writing. A pilot study was conducted early in 2021 as part of Wageningen University’s ongoing distance learning programme, offering a chance to evaluate and refine the course at an early stage. CANA is made up of a group of extremely enthusiastic and committed African scientists who themselves completed the first pilot study. With support from Wageningen University and ICONIC, CANA then planned and led two further pilot courses modified to be sensitive to the African context, offered in West Africa later in 2021 and 2022. Further courses have been offered in 2023 and 2024, with broader representation from across Africa (Kenya, Ghana, Nigeria, Botswana, Uganda, Rwanda and Ethiopia). The team has also recruited participants from previous cohorts as assistants to support them in the course delivery.

Participants have expressed how beneficial the course has been for them, addressing specific challenges experienced in LMICs and enabling them to feel more confident in writing grant proposals. The online course will be offered each year to African scientists who want to gain knowledge and experience with writing grant proposals in this specialist area. 

In recognition of the importance of building research capacity in Africa, the activity has received support from the UK Nutrition Society (in 2022 and 2024) and the Love Hope Strength Foundation (in 2023).

Developing a Quality Assurance Framework for Cancer and Nutrition

There is increasing acknowledgement of the absence of quality assurance data internationally for the formulation of secure policy, particularly in the area of cancer and nutrition, and this has been identified as a fundamental constraint which limits progress towards every aspect of the UN Sustainable Development Goals.

For research studies, the training and oversight of those taking measurements is usually conducted with care, but this is not necessarily the case in the context of routine care, even though life and death decisions might be based on the interpretation of these measurements. More recently, there has been promotion of digital health platforms in which measurements taken as part of routine care by persons of uncertain skill and competency are to be used either individually or aggregated to determine policy, for programmatic purposes and as the basis for individual clinical judgements. This raises a serious concern about the validity and utility of measures taken by staff without formal training, oversight, and some form of quality assessment. Needs have been identified for:

1. Standardisation of measurement methodology and protocols
2. Defined training and demonstrable competency of those responsible for making and supervising measurements
3. Measures to be conducted within a QAF that provides the necessary structures and systems to monitor performance and fidelity against defined processes.

A Working Group of ICONIC was tasked with the development and escalation at scale of a Quality Assurance Framework, initially for anthropometry, but eventually for other markers of nutritional wellbeing. The ambition is that this should be available across sub-Saharan Africa as the Quality Assurance Framework and Nutrition for Africa (QAFANA) for the collection and curation of secure nutritional data that can be used with confidence for policy, planning, monitoring and evaluation in critical areas of the health sector (cancer), the education sector (childhood obesity) and the agricultural sector (food and nutrition security).

As a first step, colleagues from Ghana spent two weeks at the University of Southampton for training and competency assessment required to the level of trainer. During their stay, the Working Group had the opportunity to also discuss the wider introduction of QAFANA: its scope, nature and strategy.

Two recognised Centres for Nutritional Assessment (CNAs) are now being established in host academic institutions in Ghana: Kwame Nkrumah University of Science and Technology (KNUST) in Kumasi and the University of Health and Allied Sciences (UHAS) in Hohoe. The necessary quality assurance structures, systems and processes are also being developed. Dr Reginald Annan and Mrs Patience Dormediame have since led the training and competency assessments of students and national service personnel in these institutions – they continue to build and assess competency amongst these individuals and core teams have been established within both CNAs. The experience is subject to the appropriate monitoring and evaluation, which is being used to help assess and refine the training programme.

In October 2023, Dr Stephen Wootton from the University of Southampton, visited Ghana on behalf of ICONIC to sign off on both CNAs and to seek continued support from the senior leadership in each institution. Whilst there, Dr Wootton also supported colleagues in hosting a symposium before the Conference on Nutrition and Dietetics (COND) to create awareness of QAFANA and its objectives among the Ghana Association of Nutritionists and Dieticians (GAND). The symposium successfully created awareness and generated support and engagement at the national level. Senior representatives from three other Universities in Ghana indicated they wished to work collaboratively with colleagues in UHAS and KNUST – The University of Accra in Legon, The University of the Cape Coast and The University for Developmental Studies in Tamale.

In 2022, financial support was secured from the World Cancer Research Fund (WCRF) International to fund the first year of the activity – Dr Panagiota Mitrou from WCRF said “WCRF is delighted to be able to support this important initiative and help Africa be a beacon of good practice for the rest of the world.”

The activity has also received support for a second year from the Love Hope Strength Foundation, which will support extending the activity to French-speaking African countries, including Cameroon. A second round of training, like that offered to Ghanian colleagues early in 2023 for training and competency assessment, is being planned for later in 2024. 

Nutrition in children, teenagers and young adults (CTYA)

Despite improvement in treatment and outcomes, cancer remains an important cause of death in childhood, and survivors carry significant risks to their long-term health in adult life. The response to treatment, survival and health outcomes, of children, teenagers and young people (CTYA) with cancer, is greatly improved, when attention is given to diet, nutrition and physical activity as integral to routine care. 

Establishing a Community of Practice

It is recognised that the efforts of those who are working to achieve more successful outcomes would be greatly strengthened, if relevant experience could be shared more readily, through the use of a suitable and accessible platform. ICONIC, together with the Aladina Foundation in Spain and Cancer Warriors Foundation in the Philippines, explored how this might be achieved through establishing a Community of Practice (CoP) to facilitate the exchange of knowledge and experience in this area. The WHO Knowledge Action Portal on Non-Communicable Diseases (KAP), hosted by the WHO’s Global Coordination Mechanism on the Prevention and Control of Non-communicable Diseases (GCM/NCD), offers a readily accessible web-based platform for this CoP to be developed. Four stakeholder consultations have been held since December 2023 to introduce the proposal, invite comment and seek support. 

The new community Nutrition and Cancer in Children, Teenagers and Young Adults (CTYA) is now open to all those interested in sharing knowledge and experience in relation to diet, nutrition, physical activity and cancer in CTYA. It is looking to create a sustainable collaborative network of clinicians and researchers, to seek consensus on best practices and work together to improve the routine care of young cancer patients. Over time, it will also seek to provide a space for young people with cancer and their families/carers to exchange experiences and raise concerns to be addressed.

The community pages are in the very early stages of development and over the next period ICONIC will continue working with WHO and others to establish the platform and extend engagement. A small Editorial Board has been established to help manage content and keep the platform up to date. The intention is to use the platform with discussion features to promote dialogue, as well as share resources and activity updates via a noticeboard and knowledge repositories. To develop the platform, the collective views of the community are important and the team welcomes ideas about how it might be used and what resources can be shared, for example. You can join the community and feedback any comments via the noticeboard pages.

UICC Special Focus Dialogues

Nutrition and cancer in CTYA was the focus of the first of a series of Virtual Dialogue sessions in 2021, hosted by ICONIC in collaboration with UICC. A second Special Focus Dialogue is being planned for 25th November 2024.

Digitial Session at the World Cancer Congress 2024

In collaboration with the Cancer Warriors Foundation, the World Health Organisation and the World Cancer Research Fund International, in September 2024 ICONIC hosted a digital session at the World Cancer Congress in Geneva – Co-creating a new knowledge-sharing platform on nutrition and cancer for children, teenagers and young adults (CTYA). The digital session is available to delegates on the World Cancer Congress platform until the end of the year.

School Health and Nutrition

ICONIC has contributed directly to the global school feeding initiative of the School Meals Coalition launched in 2021 with the World Food Programme as the lead agency and supported by UN Nutrition. Professor Jackson, Chair of ICONIC, sits as an observer for IUNS. ICONIC was instrumental in the formation of a Special Interest Group within the Nutrition Society and has continued to explore opportunities to collaborate with the Coalition, and its Research Consortium, to improve the health, nutrition status and wellbeing of school children across LMIC, with a focus on Africa. In October 2022, together they offered a session to celebrate the first year of the School Meals Coalition – session titled ‘Schools as a system to improve nutrition’ (available on the School Meals Coalition YouTube channel) which discussed issues affecting the delivery of school meals to children in the global south, and what strategies could be adopted to improve coverage and delivery of safe/quality school meals.

In collaboration with the Africa Nutrition Society and IMTF, ICONIC has been planning towards a Regional Workshop on School Nutrition, scheduled to take place at the University of Cape Coast, Cape Coast in October 2024, immediately before the Africa Nutrition Conference (ANC) in Ghana. This pre-conference workshop will gather experts from Africa and beyond, including academics, researchers, development partners, NGOs, and policymakers, to address the importance of school health and nutrition and the special role that professional nutritionists might play.

A formal report will be prepared following the Workshop to capture and consolidate experience to date, and to provide the basis for a plan of coordinated action.

Prehabilitation

Following publication of a report by NIHR in collaboration with Macmillan (a cancer care charity) and the Royal College of Anaesthetists “Principles and guidance for prehabilitation within the management and support of people with cancer” in 2019, ICONIC committed to applying this guidance for widened access to structured prehabilitation for people with cancer and to consider how the recommendations might be made more accessible internationally. The report called for a greater focus on prehabilitation, including nutrition, physical activity and psychological support, in the delivery of cancer care.

In December 2021, ICONIC was pleased to host the second in its series of online Special Focus Dialogues in collaboration with UICC, this one with a focus on prehabilitation and cancer: Special Focus Dialogue: Prehabilitation – Multimodal interventions to improve resilience and response to treatment in cancer | UICC. Experts came together to share their experience in developing, implementing and evaluating prehabilitation interventions. It explored how being nutritionally, physically and psychologically ‘unfit’ can influence the resilience to cancer and how multimodal prehabilitation contributes to help decreasing treatment-related morbidity, increasing cancer treatment options, and improving physical and psychological health outcomes. The session was chaired by Associate Professor Stephen Wootton and speakers included Professor Franco Carli, Dr Stefan Van Rooijen and Dr Sandy Jack. 

This was also one of the topics that formed part of ICONIC’s symposium at the 22nd IUNS International Congress of Nutrition (ICN) in Tokyo in December 2022.

The 2019 report is in the process of being reviewed and updated. ICONIC is contributing by strengthening the evidence base that informs the guidance.